The overshoot and phenotypic equilibrium in characterizing cancer dynamics of reversible phenotypic plasticity
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چکیده
منابع مشابه
The overshoot and phenotypic equilibrium in characterizing cancer dynamics of reversible phenotypic plasticity.
The paradigm of phenotypic plasticity indicates reversible relations of different cancer cell phenotypes, which extends the cellular hierarchy proposed by the classical cancer stem cell (CSC) theory. Since it is still questionable if the phenotypic plasticity is a crucial improvement to the hierarchical model or just a minor extension to it, it is worthwhile to explore the dynamic behavior char...
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ژورنال
عنوان ژورنال: Journal of Theoretical Biology
سال: 2016
ISSN: 0022-5193
DOI: 10.1016/j.jtbi.2015.11.008